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Peer-Reviewed Publication
J Comp Eff Res2026;e250198.August 31, 2026Journal Article

Validation of an all-source composite mortality endpoint in the US population.

Yanina Natanzon1, Lukas Slipski1, Mark S Walker1
1ConcertAI, LLC, Cambridge, MA 02138, USA.

Abstract

Aim: To validate ConcertAI's All Source Composite Mortality Endpoint (ASCME), which combines information from electronic health records, obituary, government and administrative claims. To compare overall survival (OS) estimates using ASCME versus a National Death Index (NDI) dataset across clinical cohorts. Materials & methods: Retrospective study of oncology real-world data, reporting sensitivity…

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