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Peer-Reviewed Publication
J Am Heart Assoc2026;e047319.August 30, 2026Journal Article

Association Between Aortic Valve Mean Gradient and TAVR Outcomes: A Perspective From a Nationwide Registry.

Matthew J Czarny1, Maeve Jones-O'Connor1, Rani K Hasan1, Faisal Rahman1, Hamza Aziz2, Michael P Robich2, Daniel Haugan3, Jon R Resar1
1Division of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.
2Division of Cardiac Surgery, Department of Surgery Johns Hopkins University Baltimore MD USA.
3Structural Heart and Aortic Medtronic Minneapolis MN USA.

Abstract

BACKGROUND: Patients with severe aortic stenosis with very low resting aortic valve mean gradient (MG) are underrepresented in transcatheter aortic valve replacement (TAVR) studies. We investigated the association of resting aortic valve MG with post-TAVR outcomes in a large nationwide cohort. METHODS: We included patients from the Society of Thoracic Surgeons/American College of Cardiology Trans…

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