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Drug Alcohol Depend Rep2026;20100469.September 1, 2026Journal Article

Exploring hormonal influences on nicotine craving and use across the perinatal period: A prospective longitudinal study.

Alicia M Allen1,2, James Baurley3, Linnea B Linde-Krieger4, Arushi Chalke5, Whitney Norris6, Xinger Xia4, Ashley H Clawson7
1National Center for Opioid and Addiction Research, Arkansas Children's Research Institute, 13 Children's Way, Slot 842, Little Rock, AR 72202, United States.
2Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, 1300 South Medical Drive, Little Rock, AR 72202, United States.
3BioRealm LLC, 19330 Rim of the World Drive, Monument, CO 80132, United States.
4School of Social Work, Arizona State University, 411 N Central Ave, #800, Phoenix, AZ 85004, United States.
5Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA.
6College of Nursing, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, United States.
7Department of Health Behavior and Health Education, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, United States.
PubMed PMC DOI PDF

Abstract

INTRODUCTION: Perinatal nicotine use is common despite well-documented adverse consequences. We examined associations between reproductive-related hormones with nicotine craving and use during the perinatal period to identify potential novel intervention points. METHODS: All participants reported use of nicotine during the perinatal period. Participants were enrolled at gestational week ≥ 36 and…

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