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Peer-Reviewed Publication
Semin Ophthalmol2026;1-13.August 29, 2026Journal Article

Visual and Refractive Outcomes of Corneal Refractive Surgery for Hyperopic and Mixed Astigmatism: A Systematic Review and Meta-Analysis.

Timoteo González-Cruces1, Francisco Javier Aguilar-Salazar1, Álvaro Sánchez-Ventosa1, Marta Villalba-González1, Juan J Prados-Carmona1, Alberto Villarrubia1, Antonio Cano-Ortiz1,2,3
1Department of Anterior Segment, Cornea and Refractive Surgery, Hospital Arruzafa, Cordoba, Spain.
2Department of Health and Biomedical Sciences, Universidad Loyola, Andalucía, Spain.
3Faculty of Biomedical Sciences and Sports, European University of Andalucía, Málaga, Spain.

Abstract

TOPIC: To evaluate the visual and refractive outcomes of corneal refractive surgery (PRK, LASIK, and SMILE) for hyperopic and mixed astigmatism. The clinical question addressed was: in adults with hyperopic or mixed astigmatism, how effective and safe are modern corneal refractive procedures, without alternative surgical comparators, in reducing refractive cylinder and improving uncorrected distan…

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