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Struct Heart2026;10(9):101084.September 1, 2026Journal Article

Durability Analysis of a Self-Expanding Transcatheter Aortic Valve Through 30 Years of Accelerated Wear Testing.

Guilherme Attizzani1,2, Marco Frazzetto1, Ole De Backer3,4, Danny Dvir5, Vanessa Garlepp6, Tim Kelley6, Kendra J Grubb6, Gilbert H L Tang7
1Division of Cardiology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA.
2Osaka University, Osaka, Japan.
3The Heart Center, Rigshospitalet, Copenhagen, Denmark.
4Institute of Clinical Medicine, Copenhagen University, Copenhagen, Denmark.
5Interventional Cardiology Department, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.
6Medtronic, Mounds View, Minnesota, USA.
7Department of Cardiovascular Surgery, Mount Sinai Health System, New York, New York, USA.
PubMed PMC DOI PDF

Abstract

•First reported 30-year in vitro accelerated wear testing data for a THV.•All Evolut PRO + valves met ISO hydrodynamic criteria through 20 years of testing.•At least one valve per size maintained performance through 30 years of testing.•Failures manifested in a consistent pattern, suggesting a shared mechanism.•Testing is ongoing until all valves fail.

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