Peer-Reviewed Publication
J Imaging Inform Med2026August 26, 2026Journal Article

Multimodal AI Methods for Predicting Pathologic Complete Response in Breast Cancer.

Manu Goyal1, Tanmay Shukla2, Saeed Hassanpour3
1Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. Manu.Goyal@Dartmouth.Edu.
2Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA.
3Departments of Biomedical Data Science, Computer Science, and Epidemiology, Dartmouth College, Hanover, NH, USA.

Abstract

Neoadjuvant chemotherapy (NAC) can eliminate all invasive cancer in some breast cancer patients, achieving a pathologic complete response (pCR) that is associated with a better prognosis. Prediction of pCR from pre-treatment radiology imaging is challenging but could provide immense value in the treatment planning. We propose a novel multimodal deep learning approach that combines pre-treatment dy…

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