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Peer-Reviewed Publication
J Clin Monit Comput2026August 26, 2026Journal Article

HOPFIT: A neuro-cardiovascular monitoring framework for precision sedation, anaesthesia, and resuscitation.

Andrea Lavinio1,2, Stefano Romagnoli3,4, Basil Matta5,6,7
1Perioperative, Acute, Critical Care and Emergency Medicine (PACE) Section, Department of Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. andrea.lavinio1@nhs.net.
2Departments of Intensive Care Medicine & Anaesthesia, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK. andrea.lavinio1@nhs.net.
3Department of Health Sciences, University of Florence, Florence, Italy.
4Department of Anaesthesia and Intensive Care, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
5Perioperative, Acute, Critical Care and Emergency Medicine (PACE) Section, Department of Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
6Departments of Intensive Care Medicine & Anaesthesia, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
7Masimo Corporation, Irvine, CA, USA.
PubMed DOI

Abstract

The increasing availability of advanced monitoring technologies in anaesthesia and critical care has enabled continuous assessment of neurological, haemodynamic, and oxygen delivery parameters. Despite this, integrating multiple data streams into coherent, physiology-guided clinical decisions remains challenging, and unified interpretive frameworks remain limited. To introduce the HOPFIT framework…

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