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Peer-Reviewed Publication
Food Res Int2026;242(Pt 2):119877.October 31, 2026Journal Article

Vaccinium meridionale Swartz (Agraz): A systematic review of phytochemical composition, extraction technologies, and biological effects.

Jaime Valdiviezo-Marcelo1, Nancy Maribel Arana-Torres2, William Vera3, Heber Peleg Cornelio-Santiago4, Edwin Jorge Vega-Portalatino5, Zury Sócola6, Juan Carlos Rodríguez-Soto7, Cristina Martinez-Villaluenga8, Grimaldo Wilfredo Quispe-Santivañez9, Rebeca Salvador-Reyes10
1Grupo de Investigación Tecnologías Emergentes, Investigaciones de Mercado y Comportamiento del Consumidor (TEIMEC), Universidad Nacional de Frontera, Av. San Hilarión 101, Sullana 20103, Peru. Electronic address: jvaldiviezom@unf.edu.pe.
2Laboratorio de Biotecnología Microbiana, Universidad Nacional de Frontera, Av. San Hilarión 101, Sullana 20103, Peru. Electronic address: naranat@unf.edu.pe.
3Grupo de Investigación en Desarrollo e Innovación en Industrias Alimentarias (GIDIIA), Universidad Nacional de Frontera, Av. San Hilarión 101, Sullana 20103, Peru. Electronic address: wveraj@unf.edu.pe.
4Facultad de Ciencias de los Alimentos, Universidad Le Cordon Bleu, Magdalena del Mar, 150120, Lima, Peru. Electronic address: heber.cornelio@ulcb.edu.pe.
5Laboratorio de Biotecnología Microbiana, Universidad Nacional de Frontera, Av. San Hilarión 101, Sullana 20103, Peru. Electronic address: evega@unf.edu.pe.
6Grupo de Investigación Tecnologías Emergentes, Investigaciones de Mercado y Comportamiento del Consumidor (TEIMEC), Universidad Nacional de Frontera, Av. San Hilarión 101, Sullana 20103, Peru. Electronic address: zsocola@unf.edu.pe.
7Laboratorio de Citometría, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo, Juan Pablo II Av., Trujillo 13008, Peru. Electronic address: jrodriguezs@unitru.edu.pe.
8Department of Technological Processes and Biotechnology, Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), Calle Jose Antonio Novais 6, 28040 Madrid, Spain. Electronic address: c.m.villaluenga@csic.es.
9Escuela Profesional de Ingeniería Agroindustrial, Facultad de Ingeniería, Universidad Nacional Autónoma Altoandina de Tarma, Acobamba 120701, Peru. Electronic address: gquispe@unaat.edu.pe.
10Facultad de Ingeniería, Universidad Tecnológica del Perú, Lima 150101, Peru. Electronic address: rsalvador@utp.edu.pe.
PubMed DOI

Abstract

Vaccinium meridionale Swartz (agraz) is a wild Andean berry with a rich phytochemical profile, but evidence remains fragmented and methodologically heterogeneous, limiting its technological and nutraceutical use. This systematic review synthesized studies published between 2009 and 2026 on its phytochemical composition, extraction technologies, and biological effects. Following PRISMA guidelines,…

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