Peer-Reviewed Publication
Naunyn Schmiedebergs Arch Pharmacol2026August 19, 2026Journal Article
Proteome conserved multi-epitope-based vaccine construct against Nipah virus.
Taimoor Khan1,2, Tayyab Ali1,2, Muhammad Suhaib Qudus1,2, Gadallah Mohamed1,2,3, Farukh S Sharopov4, Adam Junka1,5, Yanfang Sun6,7
1College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
2Zhejiang International Joint Laboratory of Traditional Medicine and Big Health Products Development, Hangzhou, 310018, China.
3Biochemistry Department, Faculty of Agriculture, Al Azhar University, Cairo, Egypt.
4V.I. Nikitin Institute of Chemistry of the National Academy of Sciences of Tajikistan, Dushanbe, Tajikistan.
5″PUMA″, Platform for Unique Model Applications, Department of Translative Technologies, Faculty of Pharmacy, Wroclaw Medical University, Borowska 213, 50-556, Wrocław, Poland.
6College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China. katherineyfs@zstu.edu.cn.
7Zhejiang International Joint Laboratory of Traditional Medicine and Big Health Products Development, Hangzhou, 310018, China. katherineyfs@zstu.edu.cn.
Abstract
Nipah virus (NiV) is a highly pathogenic virus with no available FDA-approved medication. Herein, immunoinformatic-based approaches may serve as a crucial method for rapid development of vaccine targeting the emerging strains of the NiV. The study utilizes immunoinformatic-based computational methodology to design multi-epitope subunit vaccine by deciphering highly conserved antigenic epitopes acr…
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