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Peer-Reviewed Publication
Contemp Clin Trials2026;108439.August 14, 2026Journal Article

A hybrid effectiveness-implementation trial to integrate precision skin cancer risk feedback in federally qualified health centers.

Steven K Sutton1, Kea Turner2, Katherine Chung-Bridges3, Susan T Vadaparampil4, Rania Abdulla5, Mariana Arevalo6, Natasha Avrilien7, Margaret M Byrne8, Edelise Endemano9, Jennifer Garcia Hernandez10, Jada G Hamilton11, Erin Lyjak12, Zoe Parrales13, Jairo Ramos14, Maritza Torres15, Brian White16, Jennifer L Hay17, Peter A Kanetsky18
1Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: Steve.Sutton@moffitt.org.
2Division of Health Systems, Policy, and Innovation, School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: Kea.turner@unc.edu.
3Health Choice Network, Miami, FL, USA. Electronic address: kchung@hcnetwork.org.
4Department of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: susan.vadaparampil@moffitt.org.
5Non-Therapeutic Research Office, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: Rania.Abdulla@moffitt.org.
6Department of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: mariana.arevalo@moffitt.org.
7Health Choice Network, Miami, FL, USA. Electronic address: navrilien@hcnetwork.org.
8Department of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: margaret.byrne@moffitt.org.
9Health Choice Network, Miami, FL, USA. Electronic address: eendemano@hcnetwork.org.
10Non-Therapeutic Research Office, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: Jennifer.garciahernandez@moffitt.org.
11Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: hamiltoj@mskcc.org.
12Non-Therapeutic Research Office, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: erin.lyjak@moffitt.org.
13Non-Therapeutic Research Office, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: zoe.parrales@moffitt.org.
14Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: Jairo.Ramos@moffitt.org.
15Tampa Family Health Centers, Tampa, FL, USA. Electronic address: mbtorres@tfhc.org.
16Tampa Family Health Centers, Tampa, FL, USA. Electronic address: bwhite@tfhc.org.
17Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: hayj@mskcc.org.
18Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: peter.kanetsky@moffitt.org.

Abstract

BACKGROUND: Skin cancers are the most common type of cancer in the United States, occur in all segments of the population, and are preventable. Our previous research with primary care patients' demonstrated interest in and efficacy of a precision prevention intervention providing feedback on MC1R risk level (higher versus average) in combination with prevention education materials relative to a st…

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