Health AI Central
Peer-Reviewed Publication
J Magn Reson Imaging2026August 12, 2026Journal Article

Uteroplacental Responses to Physiological Challenges Throughout Pregnancy Using MRI.

Esra Abaci Turk1,2, Neel Dey3,4,5, Tiantian Lei1, Henry A Feldman2,6, Elfar Adalsteinsson7,8,9, William H Barth10, Polina Golland3,7, P Ellen Grant1,2
1Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
2Harvard Medical School, Boston, Massachusetts, USA.
3Computer Science and Artificial Intelligence Laboratory (CSAIL), Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
4Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA.
5Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.
6Biostatistics and Research Design Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
7Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
8Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
9Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
10Maternal-Fetal Medicine, Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA.
PubMed DOI

Abstract

BACKGROUND: Placental MRI has shown T2* decreases during contractions and increases during maternal hyperoxia. However, how contraction-induced placental oxygenation and deformation relate to uterine deformation and differ from hyperoxia-induced responses remains unknown. PURPOSE: To quantify placental T2* and deformation changes during spontaneous non-labor uterine contractions and maternal hype…

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