Phospholipid homeostasis and gametophyte development require the glycerophosphodiester phosphodiesterases GDPD5 and GDPD6.

Meike Siebers¹, Georg Hölzl¹, Regina Wehler¹, Johannes Lerch¹, Katharina Gutbrod¹, Anna Maria Schmidt¹, Michael Melzer², Andreas J Meyer³, Peter Dörmann¹

¹Institute of Molecular Physiology and Biotechnology of Plants (IMBIO), University of Bonn, Bonn, Germany.

²Department of Physiology and Cell Biology, Leibniz Institute of Plant Genetics and Crop Plant Research, Stadt Seeland, Germany.

³Institute of Crop Science and Resource Conservation (INRES), University of Bonn, Bonn, Germany.

PubMed DOI

Abstract

Glycerophosphodiester phosphodiesterases (GDPDs) hydrolyze glycerophosphodiesters, phospholipid metabolites generated by acyl hydrolases. We analyzed the function of the two related proteins GDPD5 and GDPD6 from Arabidopsis (Arabidopsis thaliana), which are expressed during phosphate starvation and in flower organs. Heterologously expressed GDPD5 and GDPD6 hydrolyzed glycerophosphocholine and othe…

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