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Peer-Reviewed Publication
Radiol Phys Technol2026August 7, 2026Journal Article

AI-based reconstruction from low-resolution acquisitions for diffusion MRI: evaluation of FOD similarity.

Akihiro Kasahara1, Yuichi Suzuki2, Kazuki Endo2, Ryosuke Mori2, Ryutaro Yano3, Hiroshi Kusahara3, Toshihiro Hayashi2, Osamu Abe4
1Radiology Center, The University of Tokyo Hospital, Tokyo, Japan. 3619105k@gmail.com.
2Radiology Center, The University of Tokyo Hospital, Tokyo, Japan.
3Canon Medical Systems Corporation, Tochigi, Japan.
4Department of Radiology, The University of Tokyo Hospital, Tokyo, Japan.

Abstract

MRI provides essential insights into tissue microstructure, and high angular resolution diffusion imaging (HARDI) enables detailed assessment of complex white matter architecture through fiber orientation distribution (FOD) analysis. However, HARDI requires high b-values and multiple diffusion directions, leading to reduced signal-to-noise ratio (SNR) and long scan times. Conventional zero-fill in…

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