Peer-Reviewed Publication
JGH Open2026;10(8):e70444.August 1, 2026Journal Article

Yield of Synchronous Adenomas and Serrated Polyps in Patients With Positive Stool Tests (mt-sDNA or FIT): Data From the New Hampshire Colonoscopy Registry.

Joseph C Anderson1,2, William M Hisey3,4, Christina M Robinson3,4, Paul J Limburg5, Bonny L Kneedler5, Lynn F Butterly1,3,4
1Geisel School of Medicine at Dartmouth Hanover New Hampshire USA.
2White River Junction VAMC White River Junction Vermont USA.
3Department of Medicine, Section of Gastroenterology and Hepatology Dartmouth-Hitchcock Medical Center Lebanon New Hampshire USA.
4NH Colonoscopy Registry Lebanon New Hampshire USA.
5Exact Sciences Corporation Madison Wisconsin USA.

Abstract

BACKGROUND AND AIMS: Patients with synchronous conventional adenomas and serrated polyps are at increased risk for metachronous neoplasia. We used New Hampshire Colonoscopy Registry data to examine the prevalence, pathway, and severity of synchronous lesions detected on colonoscopy after positive multi-target-stool DNA (mt-sDNA) or Fecal Immunochemical Tests (FIT), compared to colonoscopies withou…

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