Health AI Central
Peer-Reviewed Publication
J Med Internet Res2026;28e77307.July 31, 2026Journal Article

Impact of Large Language Model-Based AI Tools on Physician-Patient Communication: Systematic Review and Meta-Analysis.

Sven Richter1,2, Clara Helene Buszello1, Markus Prem1, Sophia Willkommen1, Elida Hasani1, Ortrud Uckermann1, Tareq A Juratli1, Ilker Y Eyüpoglu1, Witold H Polanski1
1Department of Neurosurgery, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, Dresden, 01307, Germany, 49 3514582883.
2Else Kröner Fresenius Center for Digital Health, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
PubMed DOI

Abstract

BACKGROUND: Recent advances in large language models (LLMs) such as GPT-3/4 have spurred the development of artificial intelligence (AI) chatbots and advisory tools in medicine. These systems are posited to assist or augment physician-patient communication, potentially improving empathy, clarity, and responsiveness. However, their actual impact on communication outcomes remains uncertain. OBJECTI…

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