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Peer-Reviewed Publication
Asian J Neurosurg2026;21(3):452-462.September 1, 2026Journal Article

Villaret Syndrome: A Systematic Review.

Anis Choucha1,2, Malick Sagenly3, Matteo De Simone4,5,6, Anis Mansourt1, Manel Krouma1, Pawel Łaczak7, Yoichi Morofuji8, Nathan Beucler9
1Department of Neurosurgery, Aix Marseille University, Assistance Publique - Hôpitaux de Marseille, Hôpital de la Timone, Marseille, France.
2Division of Biomechanics and Application, Laboratory of Biomechanics and Application, UMRT24, Gustave Eiffel University, Aix Marseille University, Marseille, France.
3Department of Neurosurgery, University of Lille, Lille University Hospital, Lille, France.
4Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Via S. Allende, Baronissi, Italy.
5Department of Neurosurgery, Neurosurgery Unit, University Hospital "San Giovanni di Dio e Ruggi D'Aragona," Salerno, Italy.
6Division of Neuroanatomy, Neuroanatomy Unit, BrainLab, Mercato San Severino, Salerno, Italy.
7Department of Medicine, Medical University of Katowice, Katowice, Poland.
8Department of Neurosurgery, Showa Medical University, Tokyo, Japan.
9Neurosurgery Department, Sainte-Anne Military Teaching Hospital, Toulon Cedex, France.

Abstract

Villaret syndrome (VS) is a rare condition characterized by concurrent involvement of cranial nerves (CNs) IX-XII and the cervical sympathetic chain, suggesting a pathological process in the retrostyloid compartment. We conducted a systematic review to synthesize current knowledge regarding etiologies, clinical presentation, management strategies, and CN outcomes. A systematic search was performed…

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