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Peer-Reviewed Publication
Thorac Cardiovasc Surg2026July 30, 2026Journal Article

Applicability of Guideline-Based Aortic Intervention Thresholds in the Indian Population.

Nimrat Grewal1,2, Mohammed Idhrees3, Jedidiah Samraj3, Bashi Velayudhan3
1Amsterdam University Medical Center, University of Amsterdam, Department of Cardiothoracic Surgery, Netherlands, Amsterdam.
2Yale New Haven Hospital, Aortic Institute, Connecticut, United States, New Haven.
3SRM Institutes for Medical Science (SIMS Hospital), Institute of Cardiac and Aortic Disorders (ICAD), Tamil Nadu, India, Chennai.

Abstract

BACKGROUND: Clinical guidelines for thoracic aortopathy rely on absolute diameter thresholds to guide surveillance and prophylactic intervention. These thresholds, derived largely from Western cohorts, are applied globally, including in populations with smaller baseline vascular dimensions. METHODS: We performed a counterfactual, denominator-based analysis comparing the distribution of ascending…

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