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Peer-Reviewed Publication
JACC Case Rep2026;31(30):109186.July 29, 2026Case Reports

Wellens' Sign and Syndrome Detected With the Home Use of a Novel 12-Lead Electrocardiogram.

David E Albert1, Stavros Stavrakis2
1AliveCor, Inc, Mountain View, California, USA. Electronic address: drdave@alivecor.com.
2University of Oklahoma Health Center, Oklahoma City, Oklahoma, USA.
PubMed DOI

Abstract

BACKGROUND: Wellens' sign is a high-risk electrocardiogram (ECG) pattern associated with proximal left anterior descending artery stenoses and high risk of major adverse cardiovascular events. EARLY REPORTS SUMMARY: A man with transient chest pain remained asymptomatic including with exertion for 48 hours. His friend performs a home 12-lead ECG using a novel, artificial intelligence-enabled devic…

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