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Peer-Reviewed Publication
Small Sci2026;6(8):e70350.August 1, 2026Journal Article

Wavelet Transform-Based Atomic Force Microscopy: A Computational Paradigm for Dynamic Nanoscale Imaging and Characterisation.

Pardis Biglarbeigi1,2, Navneet Soin3,4, Amit Kumar5, Dewar Finlay6, Amir Farokh Payam6
1Department of Pharmacology & Therapeutics University of Liverpool Liverpool England UK.
2PulseAI Ltd Belfast UK.
3School of Science Computing and Emerging Technologies (SoSCET) Swinburne University of Technology Hawthorn Victoria Australia.
4School of Science RMIT University Melbourne Victoria Australia.
5School of Mathematics and Physics Centre for Quantum Materials and Technologies (CQMT) Queen's University Belfast Belfast UK.
6School of Engineering Ulster University Belfast Northern Ireland UK.

Abstract

Wavelet transform-based atomic force microscopy (WT-AFM) marks a significant paradigm shift in nanoscale imaging by enabling real-time, simultaneous computational analysis of tip-sample interactions in both the time and frequency domains. Unlike conventional AFM approaches that are limited to steady-state, single-frequency responses-the WT-AFM directly applies wavelet transform techniques to the r…

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