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Peer-Reviewed Publication
J Am Heart Assoc2026;e047930.July 25, 2026Journal Article

Health Care Resource Utilization in Transthyretin Amyloid Cardiomyopathy Compared With Non-amyloid Heart Failure and the General Population.

Justin L Grodin1, Ahmad Masri2, Richard Wright3, Jean-François Tamby4, Heather Falvey4, Liana Hennum4, Margarita Udall4, Chaitanya Badwe5, Melissa Allison5, Rakesh Ramesh6, Shradha Sanghi6, Sandesh Dev7, Jose Nativi-Nicolau8
1University of Texas Southwestern Medical Center Dallas TX USA.
2Oregon Health and Sciences University Portland OR USA.
3Pacific Heart Institute Santa Monica CA USA.
4BridgeBio Pharma, Inc. San Francisco CA USA.
5Definitive Healthcare New York NY USA.
6Definitive Healthcare Bengaluru Karnataka India.
7Arizona State University Scottsdale AZ USA.
8Mayo Clinic Jacksonville FL USA.

Abstract

BACKGROUND: Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, fatal disease associated with a substantial health care system burden. The aim of this study was to compare health care resource utilization and associated costs among individuals with ATTR-CM, with non-amyloid heart failure (HF), and without HF in the United States. METHODS: Optum's de-identified Clinformatics Data Mart…

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