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Peer-Reviewed Publication
J Perinat Med2026July 27, 2026Journal Article

Fetal growth restriction is associated with increased mechanical dyssynchrony and right-ventricular remodeling: a 2D speckle-tracking analysis.

Jana Rarbach1, Georg Schummers2, Angela Burgmair2,3, Mareike Moellers1, Kathrin Oelmeier1, Daniela Willy1, Janina Braun1, Raphael Koch4, Ralf Schmitz5
1Clinic of Obstetrics and Gynecology, University Hospital Münster, Münster, Germany.
2TOMTEC Imaging Systems GmbH, Unterschleissheim, Germany.
3Research Group Medical Technologies, Universities of Applied Sciences, Landshut, Germany.
4Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany.
5Department of Gynaecology and Obstetrics, Florence-Nightingale-Hospital, Düsseldorf, Germany.

Abstract

OBJECTIVES: This study aimed to evaluate predefined two-dimensional speckle-tracking parameters (2D-STE) to distinguish between growth-restricted fetuses (FGR) and healthy controls (FC) and to identify novel parameters using an exploratory approach. METHODS: The study comprised 112 fetuses, 56 in the FGR cohort and 56 gestational-age-matched healthy fetuses in the FC cohort. We analyzed global lo…

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