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Peer-Reviewed Publication
PLOS Digit Health2026;5(7):e0001505.July 1, 2026Journal Article

Digital phenotyping of CGM engagement reveals distinct glycemic outcomes.

Bowen Zhang1,2, Tomoki Okuno1,2, Emma Li3, Ethan Riggins4, Evie L Shen5, Joleen Vansomphone6, Estelle M Everett7,8, Gregory J Norman9, Donald R Miller10,11, Peter D Reaven2, Hua Zhou1, Jin J Zhou1,2,8
1Department of Biostatistics, University of California, Los Angeles, California, United States of America.
2Phoenix VA Health Care System (111E), Phoenix, Arizona, United States of America.
3Castilleja School, Palo Alto, California, United States of America.
4Department of Mathematics, University of California, Berkeley, California, United States of America.
5Union County Magnet High School, Scotch Plains, New Jersey, United States of America.
6Huntington Beach High School, Huntington Beach, California, United States of America.
7David Geffen School of Medicine, University of California, Los Angeles, California, United States of America.
8VA Greater Los Angeles Health Care, Los Angeles, California, United States of America.
9Dexcom, Inc., San Diego, California, United States of America.
10Department of Biomedical and Nutritional Sciences, University of Massachusetts, Lowell, Massachusetts, United States of America.
11VA Center for Medication Safety, Department of Veterans Affairs, Chicago, Illinois, United States of America.

Abstract

Benefits from continuous glucose monitors (CGMs) may depend on how devices are used over time-not only how often they are used. We linked one year of device-generated CGM wear data from 2,351 U.S. Veterans to electronic health records (EHRs) to characterize real-world usage during the first year after CGM initiation. To compare longitudinal use patterns in the presence of unsynchronized sensor rep…

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