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Peer-Reviewed Publication
J Dermatolog Treat2026;37(1):2705162.December 1, 2026Journal Article

Noninvasive imaging for the evaluation of JAK inhibitors efficacy in the management of facial vitiligo.

Maria Elisabetta Greco1, Francesca Feresin1, Alberto di Caro1, Francesca Paola Sasso1, Ilaria Proietti2, Luigi Angelo Fiorito3, Nicola Perrotta3, Giovanni Pellacani1, Concetta Potenza2, Steven Paul Nisticò1, Annunziata Dattola1
1Dermatology Unit, Department of Medical and Cardiovascular Sciences, University La Sapienza of Rome, Italy.
2Unit of Dermatology, Department of Medical-Surgical Science and Biotechnologies, Sapienza University of Rome, A. Fiorini Hospital, Terracina, Latina, Italy.
3Department of Physiology and Pharmacology "V. Erspamer", Sapienza University, Rome, Italy.

Abstract

INTRODUCTION: Vitiligo is an acquired depigmenting disorder characterized by white macules resulting from the loss of functional melanocytes. MATERIAL AND METHODS: This multicenter, real-life observational study evaluated the efficacy of topical Ruxolitinib (15 mg/g) in 100 patients with non-segmental facial vitiligo treated twice daily for three months, combining clinical scales and noninvasive…

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