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Peer-Reviewed Publication
Geroscience2026July 17, 2026Journal Article

Changes in collateral status during transfer for thrombectomy are predictive of functional outcome in large vessel occlusion stroke.

Máté Pásztor1, Esra Zhubi2, Alistair Perry3, István Szikora1, Balázs Kis4, Davide Carone3,5, George Harston3,5, Dániel Bereczki2, Tímea Takács2, Norbert Szegedi6, Csilla Rózsa7, Ildikó Vastagh8, Katalin Bihari9, Gyula Pánczél10, Pál László Salacz11, Levente Kerényi12, Zoltán Szupera13, Sándor Nardai1, Bence Gunda14
1Department of Neurointervention, Center of Neurosurgery and Neurointervention, Semmelweis University, Budapest, Hungary.
2Department of Neurology, Semmelweis University, Balassa Utca 6, 1083, Budapest, Hungary.
3Brainomix, Oxford, UK.
4Medical Imaging Clinic - Radiology, University of Debrecen Clinical Centre, Debrecen, Hungary.
5Oxford University Hospitals National Health Service Foundation Trust, Oxford, UK.
6Department of Neurology, Medical Centre, Hungarian Defence Forces, Budapest, Hungary.
7Department of Neurology, Jahn Ferenc Dél-Pesti Hospital, Budapest, Hungary.
8Department of Neurology, Bajcsy-Zsilinszky Hospital and Outpatient Clinic of Budapest, Budapest, Hungary.
9Department of Neurology and Stroke, Bács-Kiskun County Teaching Hospital, Kecskemét, Hungary.
10Department of Neurology and Stroke, Pest County Ferenc Flór Hospital, Kistarcsa, Hungary.
11Department of Neurology, Péterfy Sándor Utcai Hospital-Clinic and Trauma Centre, Budapest, Hungary.
12Department of Neurology, Fejér County Szent György Teaching Hospital, Székesfehérvár, Hungary.
13Department of Neurology and Stroke, South-Buda Central Hospital, Szent Imre Teaching Hospital, Budapest, Hungary.
14Department of Neurology, Semmelweis University, Balassa Utca 6, 1083, Budapest, Hungary. bence.gunda@gmail.com.

Abstract

Collateral circulation that determines infarct progression in large vessel occlusion (LVO) is implicitly regarded as stationary. We investigated collateral circulation changes during interfacility transfer for endovascular thrombectomy (EVT) and its association with functional outcome in anterior circulation LVO stroke. Seventy consecutive patients with middle cerebral artery occlusion transferred…

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