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Peer-Reviewed Publication
J Am Soc Echocardiogr2026July 14, 2026Journal Article

Automated Detection of Clinically Significant Mitral Regurgitation from Single-View B-mode Echocardiography Using Deep Learning.

Roman A Sandler1, Joseph Z Sokol2, Shubhadarshini Pawar3, Anna Gilgur1, Aashi Jhawer1, Shirin Sadri3, Daniel B Sokol1, Markos Muche1, Aleksandar Stojmenski1, Michael Guptan1, Joshua Penn1, Raj Makkar3, Aakriti Gupta4
1iCardio.ai Corporation, Los Angeles, United States of America.
2iCardio.ai Corporation, Los Angeles, United States of America. Electronic address: https://twitter.com/JosephSokol4.
3Karsh Center for Interventional Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
4iCardio.ai Corporation, Los Angeles, United States of America; Karsh Center for Interventional Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA. Electronic address: aakriti.gupta@csmc.edu.

Abstract

INTRODUCTION: Mitral regurgitation (MR) is one of the most prevalent valvular heart diseases, and its diagnosis traditionally relies on Doppler echocardiography, which is subject to significant variability and technical challenges. We developed and externally validated MitralVision, a deep learning model for automated classification of clinically significant MR using single-view, B-mode echocardio…

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