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Peer-Reviewed Publication
Magn Reson Med2026July 14, 2026Journal Article

Joint Reconstruction of Multiple b-Values and Multiple Directions for Accelerating Diffusion Kurtosis Imaging.

Jian Lyu1, Li Guo2, Wen Zhong3, Zhongbiao Xu4, Hai Zhao5, Mingyong Gao5, Zhifeng Xu5, Zhifeng Chen6, Hua Guo3
1Department of the Radiation Oncology Physics, Foshan Key Laboratory of Precision Therapy in Oncology and Neurology, The First People's Hospital of Foshan (The Affiliated Foshan Hospital of Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
2Clinical Research Center, Foshan Key Laboratory of Precision Therapy in Oncology and Neurology, The First People's Hospital of Foshan (The Affiliated Foshan Hospital of Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
3Center for Biomedical Imaging Research, School of Biomedical Engineering, Tsinghua University, Beijing, China.
4Department of Radiotherapy, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou, Guangdong, China.
5Department of Radiology, The First People's Hospital of Foshan (The Affiliated Foshan Hospital of Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
6Institute of Research and Clinical Innovations, Neusoft Medical Systems Co., Ltd., Hangzhou, Zhejiang, China.
PubMed DOI

Abstract

PURPOSE: While multishot interleaved echo-planar imaging (iEPI) enables higher resolution diffusion kurtosis imaging (DKI) compared to single-shot EPI, its clinical application is hindered by the lengthy acquisition time. This study proposes a novel model-based reconstruction approach to accelerate iEPI DKI acquisition. THEORY AND METHODS: The proposed model-based framework directly estimates DKI…

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