Enhanced risk stratification in hypertrophic cardiomyopathy through the integration of extracellular volume fraction on cardiovascular magnetic resonance.

Hyun-Jung Lee¹, Seo-Yeon Gwak², Suji Lee³, Kyu Kim⁴, Iksung Cho⁴, Chi Young Shim⁴, Byoung Wook Choi^3,5, Jong-Won Ha⁴, Young Jin Kim³, Geu-Ru Hong⁴

¹Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.

²Division of Cardiology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.

³Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

⁴Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.

⁵Phantomics Inc., Seoul, Korea.

PubMed DOI

Abstract

AIMS: This study investigated the incremental prognostic value of cardiovascular magnetic resonance (CMR)-derived extracellular volume fraction (ECV), a marker of diffuse interstitial fibrosis, beyond late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM). METHODS AND RESULTS: We analysed 990 consecutive HCM patients (median age 58 years, male 68.3%) who underwent CMR between 2012…

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