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Plast Reconstr Surg Glob Open2026;14(7):e7894.July 1, 2026Journal Article

Longevity and Volume Expansion of Hyaluronic Acid Dermal Fillers: A Cross-sectional 3-dimensional Magnetic Resonance Imaging Study.

Alia Issa1,2, Meydan Ben Ishai2,3,4, Caroline L Wilde2, Adam Bull2,3, Michelle Khan2, Konstantina Sorkou2, Dalia Blumgart5, Simon Morley6, Daniel G Ezra2,7
1From the Moorfields Eye Hospital Dubai, Dubai, United Arab Emirates.
2The Ezra Clinic, London, United Kingdom.
3Manchester Royal Eye Hospital, Manchester, United Kingdom.
4Rabin Medical Center, Aviv, Israel.
5UCL Medical School, University College London, London, United Kingdom.
6University College London Hospitals NHS Foundation Trust, London, United Kingdom.
7Moorfields Eye Hospital NHS Trust, London, United Kingdom.
PubMed PMC DOI PDF

Abstract

BACKGROUND: This investigation aims to analyze the volumetric expansion of injectable facial fillers over time using volumetric magnetic resonance imaging (MRI) analysis. METHODS: A retrospective cross-sectional study of 14 patients with a recorded history of filler injections underwent quantitative MRI evaluations. The volume measured was then compared with the documented volume of filler inject…

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