Peer-Reviewed Publication
Front Digit Health2026;81814015.January 1, 2026Journal Article
Selecting medical research data platforms for translational biomedical research: a five-tier overview and requirement-weighted assessment framework.
Marc Jacobs1, Samad Goudarzi1, Jan Stücke2, Robin Röhm2, Timo Kanninen3, Tero Oinonen3, Petra Ritter4, Michael Schirner4, Fabian Prasser5, Arman Bhagwagar6, Bernd Matzenbach6, Hartmut Schultze7,8, Joachim Schultze7,8, Mathias Göschl9, Henrik Matthies10, Kenneth R Evans11, Moyez Dharsee11, Christian Stephan12, Marvin Belz12, Philip Gribbon13, Katja Herzog13, Chester Chen14, David Ruau14, Ittai Dayan15, Adrish Sannyasi15, Dieter Kranzlmüller16, Naweiluo Zhou16, Jens Warfsmann17, Martin Hoffmann17, Rudi Schmidt18, Martin Hofmann-Apitius1
1Bioinformatics Department, Fraunhofer-Institute for Algorithms and Scientific Computing (SCAI), Sankt Augustin, Germany.
2Apheris AI GmbH, Berlin, Germany.
3BC Platforms, Espoo, Finland.
4Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charité, Berlin, Germany.
5Center of Health Data Sciences, BIH @ Charité, Berlin, Germany.
6DNANexus, Mountain View, CA, United States.
7Deutsches Zentrum für Neurodegenerative Erkrankungen, Bonn, Germany.
842Hills GmbH, Königswinter, Germany.
9HiGHmed e.V., Heidelberg, Germany.
10HONIC Health Data Technologies GmbH, Neckarsulm, Germany.
11Indoc Systems, Toronto, ON, Canada.
12IQVIA, Bochum, Germany.
13Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Hamburg, Germany.
14NVIDIA, Santa Clara, CA, United States.
15RHINO Federated Computing, Boston, MA, United States.
16Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences and Humanities, Garching, Germany.
17Division of Personalized Tumor Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Regensburg, Germany.
18Bonn-Aachen International Center for Information Technology (B-IT), University of Bonn, Bonn, Germany.
Abstract
INTRODUCTION: Translational biomedical research is increasingly collaborative and multimodal, making secure, high-quality data capture, curation, and analytics a major challenge. This work aims to provide an overview of existing medical research data platforms to support informed platform selection for translational biomedical research.
METHODS: As part of an ongoing Fraunhofer Request for Propos…
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