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Peer-Reviewed Publication
AJNR Am J Neuroradiol2026June 29, 2026Journal Article

Validation of an Automated ASPECTS Software via a Multi-Reader Multi-Case Clinical Reader Study.

Rotem Golan1, Kauê T N Duarte2, Chris C Duszynski2, Luis A Souto Maior Neto2, Bijoy K Menon2
1From the Circle Cardiovascular Imaging Inc. (R.G., C.C.D., L.A.S.M.N.), Calgary, AB, Canada; Department of Clinical Neurosciences (K.T.N.D., B.K.M.), Hotchkiss Brain Institute (K.T.N.D., B.K.M.), Department of Clinical Neurosciences (B.K.M.), Cumming School of Medicine and Department of Community Health Sciences (B.K.M.), University of Calgary, Calgary, AB, Canada. rotem.golan@circlecvi.com.
2From the Circle Cardiovascular Imaging Inc. (R.G., C.C.D., L.A.S.M.N.), Calgary, AB, Canada; Department of Clinical Neurosciences (K.T.N.D., B.K.M.), Hotchkiss Brain Institute (K.T.N.D., B.K.M.), Department of Clinical Neurosciences (B.K.M.), Cumming School of Medicine and Department of Community Health Sciences (B.K.M.), University of Calgary, Calgary, AB, Canada.

Abstract

BACKGROUND: Rapid, accurate detection of early ischemic changes (EIC) on non-contrast computed tomography (NCCT) is critical for the triage and treatment of acute ischemic stroke (AIS) patients, yet NCCT interpretation remains challenging due to low soft-tissue contrast and inter-reader variability. MATERIALS AND METHODS: This study validates StrokeSENS ASPECTS, a fully automated AI-based softwar…

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