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Peer-Reviewed Publication
J Cardiovasc Electrophysiol2026June 25, 2026Journal Article

PVC Variability and Impact on Meeting Expert Consensus Cutoffs of ≥ 10 000 PVCs/Day and ≥ 15% PVCs.

Richard S Amara1, Justin Brilliant1, Jason Appelbaum1, Ameer Abutaleb2, Rama Vunnam1, Stephen R Shorofsky1, Jeffrey N Rottman1, Ardit Kacorri3, Timm M Dickfeld1
1Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
2George Washington Transplant Institute, Washington, DC, USA.
3iRhythm Technologies Inc., San Francisco, California, USA.

Abstract

BACKGROUND: Frequent PVCs have been associated with a reversible cardiomyopathy. Cutoffs of ≥ 10 000 PVCs/day and ≥ 15% PVCs have been suggested by the 2014 EHRA/HRS/APHRS and 2017 AHA/ACC/HRS Expert Consensus guidelines, respectively, for PVC suppression. OBJECTIVE: To investigate the impact of PVC variability on meeting guideline-suggested PVC thresholds. METHODS: Six hundred and six patients…

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