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Peer-Reviewed Publication
J Med Econ2026;29(1):1779-1799.December 1, 2026Journal Article

Budget impact of implementing AI-enabled chest X-ray based incidental pulmonary nodule detection for early lung cancer diagnosis: models from Colombia, Costa Rica, Mexico, Thailand and Vietnam.

Albertus Constantijn Sloof1,2, Sofia Sheveleva1, Saniya Pawar3, Bhargava Reddy3, Bruna Dirodi4, Bibiana Paola Garcia Peña4, Rosario Mata Coto4, Sebastián Cortés4, Danai Chinnacom4, Hoai Thanh Van Pham4
1Asc Academics, Groningen, The Netherlands.
2Department of Health Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
3Qure.AI, Mumbai, India.
4Astrazeneca Plc.

Abstract

OBJECTIVE: To assess the budget impact of incidental pulmonary nodule (IPN) detection using an artificial intelligence-software for chest X-ray (CXR) interpretation - qXR - for early lung cancer (LC) detection in Vietnam, Colombia, Thailand, Costa Rica, and Mexico. METHODS: Country-specific hybrid decision-tree and budget impact models were developed from the public payer perspective over a 5-yea…

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