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Peer-Reviewed Publication
Eur Radiol2026June 18, 2026Journal Article

Impact of adjunctive quantitative analysis on visual interpretation of amyloid PET: a multiple tracer, multicentre study.

Seunggyun Ha1, Byungwook Choi2, Soo Jin Kwon1,3, Sungmin Kang2, Junik Son4, Shin Young Jeong5, Sang-Woo Lee5, Yeong Sim Choe6, Donghyeon Kim6, Chae Moon Hong7
1Division of Nuclear Medicine, Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
2Department of Nuclear Medicine, Daegu Catholic University Hospital, Daegu Catholic University School of Medicine, Daegu, Republic of Korea.
3Division of Nuclear Medicine, Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
4Department of Nuclear Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea.
5Department of Nuclear Medicine, Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
6Research Institute, Neurophet Inc., Seoul, Republic of Korea.
7Department of Nuclear Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea. cmhong@knu.ac.kr.

Abstract

INTRODUCTION: Visual amyloid positron emission tomography (PET) interpretation is standard for detecting cerebral amyloid-β but is limited by subjectivity, inter-reader variability, and tracer heterogeneity. We evaluated the impact of adjunctive quantitative analysis in real-world clinical practice. MATERIALS AND METHODS: This retrospective multicentre study included patients who underwent amyloi…

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