Impact of phospholipase A2 hydrolysis on triplet-triplet annihilation upconversion liposomes.

Amrutha Prabhakaran¹, Nirod Kumar Sarangi¹, Colm Smith¹, Ruben Arturo Arellano Reyes¹, Tia E Keyes¹

¹School of Chemical Sciences and National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland. tia.keyes@dcu.ie.

PubMed DOI

Abstract

Triplet-triplet annihilation upconversion (TTA-UC) liposomes are of emerging interest because of their potential bioapplications in biosensing/imaging and light-driven therapeutic delivery. However, a potential challenge in vivo is their stability, since liposomes are prone to enzymatic degradation. Here, for the first time, we examine the impact of phospholipase hydrolysis on TTA-UC in liposomes.…

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