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Peer-Reviewed Publication
Patient Educ Couns2026;150109743.September 1, 2026Journal Article

Minimizing nocebo side effects in health care: The unrecognized role of patient involvement.

Emily K Spotts1, Matthew T Tull2, Kate Faasse3, Andrew L Geers4
1Department of Psychology, University of Toledo, Toledo, OH, USA. Electronic address: Emily.Spotts@utoledo.edu.
2Department of Psychology, University of Toledo, Toledo, OH, USA; Lyra Health, Burlingame, CA, USA.
3School of Psychology, University of New South Wales, Kensington, Australia.
4Department of Psychology, University of Toledo, Toledo, OH, USA.

Abstract

OBJECTIVE: Nocebo side effects occur when patient expectations worsen negative psychological and physiological responses to medical treatments. This phenomenon can significantly impact patient experiences and outcomes across a broad range of health conditions and treatment types. Interventions are necessary to help patients avoid and minimize nocebo side effects, and in this paper, we explore a ne…

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