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Peer-Reviewed Publication
Front Cardiovasc Med2026;131808900.January 1, 2026Journal Article

Sex-Specific trajectories of arterial stiffness: a large-scale description of 38 million real-world pulse wave velocity measurements.

Benjamin Vittrant1, Pierre Boutouyrie2,3, Rosa Maria Bruno2,3
1Data Science, Withings, Issy-les-Moulineaux, France.
2Inserm PARCC, Université Paris Cité, Paris, France.
3Pharmacology Department, Hôpital Européen Georges Pompidou, DMU CARTE, Assistance Publique Hôpitaux de Paris, Paris, France.
PubMed PMC DOI PDF

Abstract

INTRODUCTION: Arterial stiffness, measured by Pulse Wave Velocity (PWV), is a critical marker of cardiovascular risk. However, current reference values are often derived from limited clinical cohorts. This study aims to establish large-scale normative trajectories for PWV using real-world data. METHODS: We analyzed anonymized data from 38,648,329 measurements collected via Withings smart scales i…

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