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Peer-Reviewed Publication
J Med Econ2026;29(1):1431-1444.December 1, 2026Journal Article

Impact of Crohn's perianal fistulas on healthcare resource utilization: a US chart review study.

Parakkal Deepak1, Serre-Yu Wong2, Alyssa M Parian3, Mark Sun4, Pradeep Nazarey5, Susan Cazzetta5, Brian Terreri5, Beni Turner6, Bridgett Goodwin5
1Washington University School of Medicine, St. Louis, MO, USA.
2Icahn School of Medicine at Mount Sinai, New York, NY, USA.
3Johns Hopkins University School of Medicine, Baltimore, MD, USA.
4University of Minnesota, Minneapolis, MN, USA.
5Takeda Pharmaceuticals USA, Inc., Lexington, MA, USA.
6TriNetX, LLC, Cambridge, MA, USA.

Abstract

AIM: Perianal fistulas are a common complication of Crohn's disease. Despite the current treatment options, fistula recurrence/treatment failure rates are high. The aim of this study was to assess healthcare resource utilization (HCRU) among patients with new, persistent, and recurrent Crohn's perianal fistulas (CPF) in the USA. METHOD: A retrospective, multi-site medical chart review was conduct…

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