Glucose-Derived Personalized HbA1c Correction (GDAC) Study to Improve Alignment Between CGM-Derived Metrics and HbA1c in Different Individuals and Racial Groups With Diabetes: Implications for Clinical Practice.

Ramzi A Ajjan¹, Pratik Choudhary², Yongjin Xu³, Timothy C Dunn³

¹The LIGHT Laboratories, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K.

²Diabetes Research Centre, University of Leicester, Leicester, U.K.

³Clinical Affairs, Abbott Diabetes Care, Alameda, CA.

PubMed DOI

Abstract

OBJECTIVE: Glycated hemoglobin (HbA1c) and average glucose (AG) can show discordance due to personal variations in red blood cell (RBC) physiology, creating management difficulties. Our aims were to understand the size of the problem and refine this glycemic metric by adjusting for personal differences in RBC characteristics. RESEARCH AND DESIGN AND METHODS: A 26-week prospective study was conduc…

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