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Peer-Reviewed Publication
J Cardiovasc Magn Reson2026;28(2):102753.June 4, 2026Journal Article

Reference ranges for myocardial native T1, T2, and extracellular volume at 5.0T cardiac magnetic resonance imaging in healthy adults.

Shiyu Wang1, Xianling Qian1, Yali Wu1, Xiyin Miao1, Ziyun Guan2, Dong Wang2, Rui Wang2, Yinyin Chen1, Ling Chen1, Zhuolin Liu1, Shaofeng Duan3, Lin Tian4, Hang Jin5, Mengsu Zeng6
1Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China; Shanghai Institute of Medical Imaging, Shanghai, China.
2United Imaging Healthcare, Shanghai, China.
3Collaborative Innovation Department, United Imaging Healthcare, Shanghai, China.
4Circle Cardiovascular Imaging Inc., Calgary, Alberta, Canada.
5Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China; Shanghai Institute of Medical Imaging, Shanghai, China. Electronic address: jin.hang@zs-hospital.sh.cn.
6Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China; Shanghai Institute of Medical Imaging, Shanghai, China. Electronic address: zeng.mengsu@zs-hospital.sh.cn.

Abstract

BACKGROUND: A 5.0T Cardiovascular magnetic resonance (CMR) offers potential advantages over 3.0T systems, including improved signal-to-noise ratio and spatial resolution. Although myocardial T1 and T2 mapping techniques are increasingly applied in clinical practice, reference ranges for these parameters at 5.0T have not yet been established. The aim of this study is to determine normal reference v…

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