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Peer-Reviewed Publication
Cardiovasc Intervent Radiol2026June 2, 2026Journal Article

A Promptable 3D-CT Foundation Model-Based Approach for Pulmonary Embolism.

K Le Floch1,2, E Ferreres3, J Khlaut4,3, A Prat3, L Alberge3, L Machado3,5, D Tordjman3, X Guerra4, P Hérent3,6, P Manceron3, M Sapoval7, T Boeken8
1Department of Vascular and Oncological interventional Radiology, Hôpital Européen Georges Pompidou, HeKA PRAIRIE-PSAI, INRIA Paris, Paris, France. korentin.lefloch@aphp.fr.
2, Raidium, Paris, France. korentin.lefloch@aphp.fr.
3, Raidium, Paris, France.
4Department of Vascular and Oncological interventional Radiology, Hôpital Européen Georges Pompidou, HeKA PRAIRIE-PSAI, INRIA Paris, Paris, France.
5Department of Radiology, Beaujon Hospital, Clichy, France.
6Department of Radiology, Saint-Denis, France.
7Department of Vascular and Oncological interventional Radiology, Hôpital Européen Georges Pompidou, HeKA PRAIRIE-PSAI, INRIA Paris, Paris, France. marc.sapoval2@aphp.fr.
8Department of Vascular and Oncological interventional Radiology, Hôpital Européen Georges Pompidou, HeKA PRAIRIE-PSAI, INRIA Paris, Paris, France. tom.boeken@aphp.fr.

Abstract

PURPOSE: Blood clot volume (BCV), defined as the total three-dimensional (3D) volume of the thrombus on computed tomography angiography (CTA), is an objective biomarker of pulmonary embolism (PE) severity whose clinical use is limited by time-consuming manual segmentation. This study evaluates ClotIA (Clot Interventional AI), a foundation model (FM)-based approach designed for rapid and interactiv…

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