AI assisted detection of large vessel occlusion on non-contrast CT: multinational validation and reader study.

Leonard Sunwoo¹, Wi-Sun Ryu², Karen Buch³, John Conklin³, William Mehan³, Matthew Nicholas Desalvo⁴, Erik Loken⁴, Sandra Rincon³, Tatiana Rocha⁴, Marc Succi³, Myungjae Lee², Dongmin Kim², Nak-Hoon Kim⁵, Jung-Hoon Han⁶, Kyubong Lee⁶, Younbeom Jeong¹, Hyesu Yun⁶, Gwanhu Kim¹, Byeongcheon Lee⁵, Yoona Ko⁵, Cheolho Kwon¹, Roh-Eul Yoo⁷, Philip Gorelick⁸, Hee-Joon Bae⁵, Chi Kyung Kim⁹, Beom Joon Kim¹⁰

¹Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea (the Republic of).

²Artificial Intelligence Research Center, JLK, Seoul, Korea (the Republic of).

³Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA.

⁴Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

⁵Department of Neurology and Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea (the Republic of).

⁶Department of Neurology, Korea University Guro Hospital, Seoul, Korea (the Republic of).

⁷Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea (the Republic of).

⁸Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

⁹Department of Neurology, Korea University Guro Hospital, Seoul, Korea (the Republic of) kim.bj.stroke@gmail.com ckkim7@korea.ac.kr.

¹⁰Department of Neurology and Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea (the Republic of) kim.bj.stroke@gmail.com ckkim7@korea.ac.kr.

PubMed DOI

Abstract

OBJECTIVE: Early detection of large vessel occlusion (LVO) on non-contrast CT (NCCT) could accelerate stroke triage, but NCCT based artificial intelligence (AI) algorithms lack multinational validation and evidence of impact on clinician performance. We aimed to validate a machine learning based LVO detection algorithm across multinational cohorts and evaluate its impact on clinicians' diagnostic…

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