Choriocapillaris Flow-Enriched Prediction of Retinal Sensitivity Using OCT-Derived Biomarkers in Intermediate Age-Related Macular Degeneration.

Johannes Schrittwieser¹, Lukas Kuchernig¹, Virginia Mares¹, Irene Steiner², Klaudia Birner¹, Florian Frommlet², Enrico Borrelli^3,4, Hrvoje Bogunović⁵, Stefan Sacu¹, Gregor S Reiter¹

¹Department of Ophthalmology and Optometry, Medical University of Vienna, 1090 Vienna, Austria.

²Medical University of Vienna, Center for Medical Data Science, Institute of Medical Statistics, 1090 Vienna, Austria.

³Department of Surgical Sciences, University of Turin, 10124 Turin, Italy.

⁴Department of Ophthalmology, "City of Health and Science" Hospital, 10126 Turin, Italy.

⁵Institute of Artificial Intelligence, Center for Medical Data Science, Medical University of Vienna, 1090 Vienna, Austria.

PubMed PMC DOI PDF

Abstract

Objectives: To assess the association of structural biomarkers derived from optical coherence tomography (OCT) and choriocapillaris (CC) flow information with point-wise retinal sensitivity (PWS) measured by microperimetry (MP) in intermediate age-related macular degeneration (iAMD). Methods: Patients with iAMD received imaging with spectral-domain (SD)-OCT (Spectralis, Heidelberg Engineering) and…

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