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Peer-Reviewed Publication
Phytother Res2026;40(7):4532-4555.July 1, 2026Journal Article

Unlocking the Therapeutic Potential of Ganoderma lucidum: From Bioactive Compounds to Clinical Translation.

Gadallah Mohamed1,2,3, Zhixin Sun4, Lifan Yu1,2, Adam Junka5, Ruixin Bei1,2, Gautam Sethi6,7, Mingzhe Yu1,2, Yanfang Sun1,2
1College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
2Zhejiang International Joint Laboratory of Traditional Medicine and Big Health Products Development, Hangzhou, China.
3Biochemistry Department, Faculty of Agriculture, Al Azhar University, Cairo, Egypt.
4School of Social Sciences, Lingnan University, Hong Kong, China.
5Platform for Unique Models Application, Department of Pharmaceutical Microbiology and Parasitology, Wroclaw Medical University, Wrocław, Poland.
6Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
7NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Abstract

Ganoderma lucidum, a revered medicinal mushroom with a rich history in traditional East Asian medicine, has garnered significant scientific attention for its diverse pharmacological properties. This comprehensive review synthesises recent advancements in understanding the phytochemistry, biological activities and therapeutic applications of G. lucidum . We delve into the intricate composition of i…

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