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Peer-Reviewed Publication
Sci Rep2026May 12, 2026Journal Article

Technical performance of L3 skeletal muscle area (SMA) measurement on CT for L3 skeletal muscle index (L3SMI) assessment.

Hubert Beaumont1, Emilie Khayat2, Alexandre Thinnes2, Antoine Iannessi2
1Median Technologies, Les Deux Arcs, 1800 Route Des Crêtes, 06560, Valbonne, France. hubertbeaumont@hotmail.com.
2Median Technologies, Les Deux Arcs, 1800 Route Des Crêtes, 06560, Valbonne, France.

Abstract

This study aims at documenting the technical performances of the Skeletal Muscle Index at the L3 vertebra (L3SMI). In this retrospective multicenter study, we used TotalSegmentator freeware to segment muscles in axial CT scans at the L3 vertebra level and measure Skeletal Muscle Area (SMA). A dataset of 100 cancer patients (lung, colorectal, adrenal, pancreatic) was analyzed for accuracy, reproduc…

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