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Peer-Reviewed Publication
Mayo Clin Proc Digit Health2026;4(2):100355.June 1, 2026Journal Article

Artificial Intelligence-Enhanced Cardiac Point-of-Care Ultrasound: A Prospective Single-Arm Study.

Lior Fisher1, Michael Fiman2, Yuval Yarkoni1, Ella Segal1, Boris Fishman1,3, Kobi Faierstein1, Noa Rubin2, Adiel Am-Shalom2, Howard Amital3, Qiong Zhao4, Smadar Kort5, Praveen Mehrotra6, Ehud Schwammenthal1,2, Robert Klempfner1,2,3, Eyal Zimlichman1,3, Ehud Raanani1,2,3, Elad Maor1,2,3
1Leviev Cardiovascular Institute, Sheba Medical Center, Tel-Aviv University, Tel-Aviv, Israel.
2AISAP.ai, Ramat-Gan, Israel.
3Faculty of Medicine, Sheba Medical Center, Tel-Aviv University, Tel-Aviv, Israel.
4Inova Heart and Vascular Institute, Falls Church, VA.
5Stony Brook Heart Institute, Stony Brook, NY.
6Thomas Jefferson University Hospital, Philadelphia, PA.

Abstract

OBJECTIVE: To evaluate the clinical utility of combining artificial intelligence (AI) with handheld focused cardiac ultrasound (FoCUS) performed by noncardiologist physicians in clinical care settings. PATIENTS AND METHODS: In this prospective, single-arm study conducted from July 1, 2022, through December 31, 2023 (ClinicalTrials.gov NCT05455541), 660 adult patients presenting to the emergency d…

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