Peer-Reviewed Publication
BMJ Glob Health2026;11(5)May 4, 2026Journal Article

Cost-effectiveness of in-kind nutritional support for impoverished persons with tuberculosis to reduce mortality and disengagement from care in India: a modelling study.

Julia Gallini1, Urvashi B Singh2,3, Madolyn Dauphinais4,5, Sonali Sarkar6, Madeline Carwile4, Rakesh Kumar7, Raghuram Rao2, Aparna Chaudhary8, C Finn McQuaid9, Kimberly Maloomian10, Srishti Sinha11,12, Saurabh Mehta12,13, David W Dowdy14, Anne F Liu15, Benjamin P Linas4, C Robert Horsburgh16, Laura F White1, Pranay Sinha17,18
1Department of Biostatistics, Boston University, Boston, Massachusetts, USA.
2National Tuberculosis Elimination Programme, New Delhi, India.
3Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
4Section of Infectious Diseases, Boston Medical Center, Boston, Massachusetts, USA.
5University of Massachusetts Chan School of Medicine, Worcester, Massachusetts, USA.
6Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
7Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India.
8Wadhwani Institute for Artificial Intelligence, Mumbai, India.
9Department of Infectious Disease Epidemiology and Dynamics, London School of Hygiene and Tropical Medicine, London, UK.
10Harvard Medical School, Boston, Massachusetts, USA.
11Program in International Nutrition, Cornell University Division of Nutritional Sciences, Ithaca, New York, USA.
12Cornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, Ithaca, New York, USA.
13Division of Medical Informatics, St John's Research Institute, Bengaluru, India.
14Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA.
15Department of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts, USA.
16Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA.
17Section of Infectious Diseases, Boston Medical Center, Boston, Massachusetts, USA psinha@bu.edu.
18Section of Infectious Diseases, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.

Abstract

BACKGROUND: Undernutrition is a leading risk factor for tuberculosis (TB) mortality and poor treatment outcomes. We evaluated the cost-effectiveness of providing in-kind nutritional support to impoverished persons with TB (PWTB) in India. METHODS: We developed a Markov model comparing standard care with a household-level nutritional food-basket intervention. Model parameters were informed from sy…

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