Enhancing aerosol delivery in asthma and COPD: a comparison of MDI, valved holding chamber, and DPI systems using functional respiratory imaging (FRI).

Mark W Nagel¹, Hosein Sadafi², Jason A Suggett³

¹Trudell Medical International, London, ON, N5V 5G4, Canada. mnagel@trudellmed.com.

²Fluidda N.V., Groeningenlei 132, Kontich, 2550, Belgium.

³Trudell Medical International, London, ON, N5V 5G4, Canada.

PubMed PMC DOI PDF

Abstract

Effective respiratory therapy relies heavily on inhaler device efficiency and patient technique. While device performance is well-documented in idealized induction ports, there remains a critical lack of data integrating patient-specific disease states to compare pressurized metered-dose inhaler (MDI) and valved holding chamber (VHC) efficiency against legacy dry powder inhaler (DPI) formulations.…

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