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Peer-Reviewed Publication
J Comp Eff Res2026;15(5):e250181.May 1, 2026Journal Article

Switching adult patients with spasticity from onabotulinumtoxinA to abobotulinumtoxinA: a real-world data analysis across three US-based treatment centers.

Nate Way1, Edward Dabrowski2, Mitchell Paulin3, Martin Taylor4, John Madden5, Amandeep Mann5, Jonathan Bouchard5
1Real World Evidence, Cerner Enviza, an Oracle Company, Malvern, PA 19301, USA.
2Beaumont Health, Royal Oak, MI 48073, USA.
3The Center for Tone Management of the Main Line, Paoli, PA 19301, USA.
4OrthoNeuro, New Albany, OH 43054, USA.
5Ipsen, Cambridge, MA 02142, USA.

Abstract

Aim: To assess patient characteristics, treatment patterns, botulinum toxin type-A (BoNT-A) costs and describe safety in adults with spasticity who switched from onabotulinumtoxinA to abobotulinumtoxinA. Materials & methods: Chart data from three US-based treatment centers was collected in patients aged ≥18 years with upper limb (ULS), lower limb (LLS) or ULS and LLS (ULS + LLS) spasticity. Eligib…

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