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Peer-Reviewed Publication
JBMR Plus2026;10(5):ziag047.May 1, 2026Journal Article

Pain medication use in patients with X-linked hypophosphatemia treated with burosumab: a retrospective real-world study.

Carolyn M Macica1, Zhiyi Li2, Ben Johnson3, Ahmed Noman4, Catherine Park4, Gina N Woods5
1University of Connecticut School of Medicine and Connecticut Children's Research Institute, Department of Research Operations and Development, Hartford, CT 06106, United States.
2Kyowa Kirin Inc., HEOR, Princeton, NJ 08540, United States.
3Kyowa Kirin International, HEOR, Marlow SL7 1HZ, United Kingdom.
4Komodo Health Inc., New York, NY 10010, United States.
5UC San Diego Health, School of Medicine, CA 92093-0602, United States.

Abstract

X-linked hypophosphatemia (XLH) is a rare, progressive phosphate-wasting disorder that leads to significant skeletal morbidity and pain. The current study used real-world administrative claims data to assess the demographic and clinical characteristics of patients with XLH related to claims for prescription pain medication (PPM) during the 12 mo before starting burosumab treatment (baseline) and e…

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