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Peer-Reviewed Publication
Sleep Breath2026;30(2)April 24, 2026Journal Article

Obstructive sleep apnea, positive airway pressure therapy, and COVID-19 outcomes.

Matthew Klimper1, Jiaxiao Shi2, Adam V Benjafield3, Kate V Cole3, Aiyu Chen2, Joanie Chung2, Jessica Arguelles1, Nathanael H Hwang1, Kendra A Becker1, Joseph B Kim1, Rosa R Woodrum1, Cecilia Portugal2, Olivia H Hwang4, Prasanth Manthena1, Dennis Hwang5
1Sleep Medicine, Kaiser Permanente Southern California, Southern California, USA.
2Department of Research and Evaluation, Kaiser Permanente Southern California, Southern California, USA.
3ResMed Science Center, ResMed Corp, San Diego, USA.
4Scaled Insights, London, England.
5Sleep Medicine, Kaiser Permanente Southern California, Southern California, USA. Dennis.X.Hwang@kp.org.
PubMed DOI

Abstract

PURPOSE: To quantify the association between obstructive sleep apnea (OSA) and COVID-19 outcomes and test whether adherence to positive airway pressure (PAP) therapy modifies this relationship. METHODS: This retrospective cohort study compared groups with and without OSA, stratified by degrees of PAP adherence (February 1, 2020 to July 31, 2020) from an integrated healthcare system (Kaiser Permane…

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